Jump ARCHES Spring 2021 Funded Grants

Jump ARCHES Spring Grants Focus on COVID-19 Vaccination and Testing Challenges & Strategies

April 12, 2021 | Champaign, IL

Seven research projects are sharing slightly more than $400,000 in funding through the Jump ARCHES research and development program to address challenges and expand on lessons learned about COVID-19 vaccinations and testing. The Jump ARCHES program is a partnership between OSF HealthCare and the Grainger College of Engineering at the University of Illinois Urbana-Champaign (U of I) and its College of Medicine in Peoria.

“As we develop new vaccines and treatments for COVID-19, it’s also important to take into account societal factors such as age, race, location, infrastructure, and how to best provide for underserved populations. We expect significant changes in how health care is delivered so that it is more accessible for all and are proud to fund projects that spearhead these developments.”

T. Kesh Kesavadas, Director, Health Care Engineering Systems Center

The funding supports research involving clinicians, engineers and social scientists to rapidly develop technologies and devices that could revolutionize medical training and health care delivery. A requirement of the grant applications was for solutions that could be deployed quickly, within four to six weeks. Investigators were also encouraged to consider how to best mitigate the impact of age, location, and social barriers in delivering quality health care to vulnerable populations.

“As we develop new vaccines and treatments for COVID-19, it’s also important to take into account societal factors such as age, race, location, infrastructure, and how to best provide for underserved populations. We expect significant changes in how health care is delivered so that it is more accessible for all and are proud to fund projects that spearhead these developments,” said T. Kesh Kesavadas, Ph.D., director of the Health Care Engineering Systems Center at the University of Illinois Urbana-Champaign.

“The outcomes of these projects will help with issues arising from the current pandemic and help physicians apply lessons learned in the post-COVID health care landscape,” said Seth Stutzman, coordinator for the Jump ARCHES grant program.

“With the UK variant now the predominant virus in the U.S., it is critical that we leverage the talent at Jump Trading Simulation and Education Center in Peoria and the brilliant minds within engineering, technology and social science at the U of I. This will help us quickly find much-needed solutions to address the challenges health care faces in developing policies and procedures for mass vaccination, health care delivery, quality and patient safety improvements,” said John Vozenilek, MD, vice president for Innovation and Digital Health at Jump and OSF HealthCare, and professor at the University of Illinois in Peoria and Urbana-Champaign.

Every Shot Counts: Development of a novel predictive model and toolkit to predict and decrease vaccine-preventable rural COVID-19 deaths

Jimeng Sun, UIUC; Scott Barrows, University of UIC, UICOMP, OSF HealthCare; Adam Cross, OSF HealthCare, UICOMP; Ann Willemsen-Dunlap, OSF HealthCare, UICOMP; and Mary Stapel, OSF HealthCare

As of April 12, 2021, 12% of the U.S. population has received at least one COVID-19 vaccine, which is below the projected 70-90% required to achieve herd immunity to the virus. This project aims to develop a predictive model to predict vaccine-preventable deaths in each county in the U.S. and the most likely reasons for vaccine hesitancy among populations. A toolkit will help guide rural populations in their decision-making about accepting the COVID-19 vaccine.

Human factors in the use of telepresence robots after the COVID-19 pandemic

Inki Kim, UIUC; Thenkurussi (Kesh) Kesavadas, UIUC; Jon Michel, OSF HealthCare; and Shandra Jamison, UIUC

The COVID-19 pandemic outbreak resulted in an increase in telemedicine visits to prevent the spread of the virus. The goal of this concept is to establish, justify and optimize a set of existing or new-use cases for telepresence robot use in telemedicine to reduce the risk of in-hospital transmission of COVID-19, as well as for continued quality of care delivery in the post-COVID-19 era.

Early insights and recommendation for implementing a COVID-19 saliva-based testing program in K-12 schools: Lessons learned from four under-resourced schools

Rebecca Lee Smith, UIUC; Thanh (Helen) Nguyen, UIUC; Nicole Delinski, OSF HealthCare; Michaelene Ostrosky, UIUC; and W. Catherine Cheung, UIUC

With the goal of successfully reopening K-12 schools and keeping them open, this proposed plan will work to gain a better understanding of the acceptability, feasibility and effectiveness of implementing saliva-based testing in under-resourced schools, as well as parental behavior of deciding to allow their children to return to in-person learning.

Voice vitals: A new approach for anxiety and depression screening in the era of COVID-19

Mary Pietrowicz, UIUC; Ryan Finkenbine, UICOMP, OSF HealthCare; and Sarah Donohue, UICOMP

Existing systems fall short in identifying and treating individuals with anxiety disorders and major depressive disorders due to a variety of issues, including people not seeking medical attention, attitudinal barriers like stigma, and structural barriers such as a lack of providers. This proposal aims to develop a prototype of machine models that can listen to speech and language and automatically screen for anxiety and depression disorders. 

COVID-19 infection levels in Central Illinois communities without access to frequent testing: A sewage monitoring and epidemiological modeling study

Thanh Helen Nguyen, UIUC; Ahmed Elbanna, UIUC; Art Schmidt, UIUC; Joanna Shisler, UIUC; and John Farrell, OSF HealthCare

New COVID-19 variants spread faster and have evaded some the vaccine-induced protective immune response in the UK and other countries. To determine whether these factors will influence the level of infection and diversity of variants in areas that lack frequent testing, this project will collect and monitor the levels and genotypes of the virus in sewage collected at selected neighborhoods. The goal is to help public health officials prepare for increased burdens on health care facilities and workers.

How to design and operate end-to-end vaccine deployment using social media, addressing supply chain allocations constraints and utilizing telemedicine

Anton Ivanov, UIUC; Subhonmesh Bose, UIUC; Albert England III, UIUC, UICOMP, OSF HealthCare; Ashen Eren Mehmet, UIUC; Ujjal Mukherjee, UIUC; Sridhar Seshadri, UIUC; Sebastian Souyris,  UIUC; and Yuqian Xu, UIUC

This idea aims to provide a comprehensive vaccine deployment strategy using data analytic frameworks. These frameworks will (1) shape population attitudes towards vaccination by reducing their uncertainty via social media channels, (2) provide a dynamic inventory management tool for perishable or sensitive goods, and (3) develop telemedicine-based solutions for convenient and sufficient post-vaccination patient support.

Building a motivational, interviewing conversational agent (MintBot) for promoting COVID-19 vaccination among people with multiple sclerosis

Jessie Chin, UIUC; Suma Bhat, UIUC; Chung-Yi Chiu, UIUC; Jared Rogers, OSF HealthCare; and Brian Laird, OSF HealthCare

Individuals with multiple sclerosis are likely to be hesitant to get the COVID-19 vaccine due to their compromised health condition. This concept aims to develop an accessible, generalizable and efficient digital health solution for promoting COVID-19 vaccination among vulnerable populations, such as people with disabilities.