Jump ARCHES Projects – Fall 2020

Latest Jump ARCHES Grants Focus on Social Sciences & Health Equity

Thirteen research projects are sharing nearly $970,000 in funding through the Jump ARCHES research and development program. The Jump Applied Research for Community Health through Engineering and Simulation (Jump ARCHES) program is a partnership between the University of Illinois (U of I) Urbana-Champaign and its College of Medicine in Peoria and OSF HealthCare.

The program supports research involving clinicians, engineers, and social scientists to develop technologies and devices that could revolutionize medical training and health care delivery.

These projects were submitted to the Fall 2020 Jump ARCHES request for proposals which concerned six unique focus areas: digital health, social and behavioral disparities, autism, neurological sciences, COVID-19, and simulation and education. This was the first Jump ARCHES request for proposals that specifically concerned social and behavioral disparities to mitigate the impact of age, location, and social barriers in delivering quality health care to vulnerable populations. Emphasis was given to proposals that addressed racism, social justice, social and implicit biases, health equity, and access to care.

“The scope of Jump ARCHES has expanded in recent years to foster collaboration with disciplines outside of engineering and medicine, such as social sciences,” said T. Kesh Kesavadas, Ph.D., director of the Health Care Engineering Systems Center at the University of Illinois Urbana-Champaign. “Technology such as AI, sensors, and simulation training can integrate with and improve outcomes in other fields in innovative ways. Above all, Jump ARCHES is striving to improve people’s lives after the disastrous impact of COVID-19 on daily life,” added Kesavadas. A special request for proposals for spring 2021 is being planned with an emphasis on solutions to the unprecedented challenges faced by our society as we develop policies and procedures in a post-COVID-19 world.

“The integration of engineering and social science promises to make the University of Illinois the world’s leading institution for innovative, technologically-driven research on social science topics, and puts social sciences in a position to advise and shape engineering efforts,” said Brent Roberts, Ph.D., director of the Center for Social and Behavioral Sciences at Illinois. He added, “The alignment of CSBS with the ARCHES program fits perfectly with a goal of our new center, to harness the technological innovations of engineering to make society better.”

“Our experience with the COVID-19 pandemic has taught us that safe and health-focused behavior has played such an important factor in mitigating the spread of the disease,” said John Vozenilek, M.D., F.A.C.E.P., V.P., and Chief Medical Officer of Jump Simulation Center in Peoria. Many of the projects represented here involve technology to improve earlier intervention which is key, particularly as we look to bring solutions for disparities in health outcomes for those who are at increased risk. It is clear there is a link between chronic health conditions and vulnerability to infectious diseases such as COVID-19. He added, “Our work is to improve prevention and early treatment for those disproportionately impacted.”

Since its inception in 2014, Jump ARCHES has awarded more than $5.46 million in funding to collaborative projects between the three institutions and across many disciplines. The effort expanded opportunities with an additional major gift in 2019.

Here are the titles, investigators, and summaries of each project:

REMOTE STATE ANXIETY DETECTION AND MONITORING USING MULTIMODAL WEARABLE SENSORS

Investigators: Manuel E. Hernandez, PhD, UIUC; Elizabeth Hsiao-Wecksler, PhD, UIUC; Richard Sowers, PhD, UIUC; Brent Roberts, PhD, UIUC; Susan Caldecott-Johnson, MD, UICOMP, OSF HealthCare Children’s Hospital of Illinois; Jean Clore, PhD, UICOMP

In frontline health care workers, recent evidence suggests increased depression, anxiety, insomnia and distress due to the COVID-19 pandemic. Even without COVID-19, physician trainees face mental health challenges as they provide care and learn clinical best practices. This project will integrate data from a suite of wearable sensors to quantify symptoms of stress and anxiety in physician trainees. The idea is to use information gleaned from sensors to monitor and potentially improve wellbeing before mental health disorders develop.

SPATIO-TEMPORAL ANALYSIS WITH TENSOR FACTORIZATION AND VISUALIZATION FOR PEDIATRIC MOBILE VACCINATION

Investigators: Jimeng Sun, PhD, UIUC; Mary Stapel, MD, OSF HealthCare; Scott Barrows, OSF HealthCare; Adam Cross, MD, OSF HealthCare; Elise Albers, OSF HealthCare; Ginger Barton, OSF HealthCare; Michelle Sheppard, OSF HealthCare; George Heintz, MSPH, MSE, UIUC; Yaroslav Daniel Bodnar, MD, OSF HealthCare, UICOMP


This project proposes to use AI technology to understand and improve the pediatric population health challenge of timely vaccination. With the help of AI, the project will visualize spatio-temporal patterns, identify critical geographic areas with the most concerning rates of under-vaccination, predict the supply need and deploy mobile immunization units to increase vaccination rates for those areas. This will improve vaccination rates in high-risk zip codes, revealing barriers around access to care and other social determinant obstacles.

TOWARD AUTOMATED DIAGNOSIS OF SEIZURES AND 3D REPRESENTATION OF SEEG CLINICAL DATA

Investigators: Matthew Bramlet, MD, UICOMP, OSF HealthCare; Brad Sutton, PhD, UIUC; Yogatheesan Varatharajah, PhD, UIUC; Andres Maldonado, MD, UICOMP, OSF HealthCare; Michael Xu, MD, PhD, UICOMP, OSF HealthCare

Some patients with seizures face debilitating effects that pharmacologic therapy cannot treat. These patients are left with surgery as their best option that requires an invasive procedure (stereotactic-electroencephalography or SEEG) to pinpoint the origin of these seizures. This project will present surgeons with a stereoscopic 3D model to give surgeons a better mental representation of where seizures are occurring. The group also wants to develop an automated interpretation algorithm of SEEG tracings, and create predictive algorithms to reduce invasive testing.

VIDEO ENHANCED NEUROLOGY (VEN)

Investigators: Chris Zallek, MD, OSF HealthCare; George Heintz, MSPH, MSE, University of Illinois at Urbana-Champaign (UIUC); and Steven Kastelein, OSF HealthCare

The number of individuals in need of neurology evaluations continues to outpace the number of available neurologists. This can create delays in diagnoses and treatment for some patients. This project will develop an infrastructure allowing clinicians to use video recorded neurological exams to reliably communicate findings to neurologists as well as improve monitoring for those already diagnosed with neurodegenerative conditions.

MEDLANG PHASE II: AN INTELLIGENT MEDICAL RECORD

Investigators: William Cope, PhD, UIUC; Cheng Xiang Zhai, PhD, UIUC; Mary Kalantzis, PhD, UIUC; Richard Tapping, PhD, University of Illinois College of Medicine Peoria (UICOMP); Yerko Berrocal, MD, UICOMP; Duncan Ferguson, VMD, PhD, UIUC; Jessica Hanks, MD, OSF HealthCare, UICOMP; Meenakshy Aiyer MD, UICOMP, OSF HealthCare

The goal of this project is to design an intelligent medical record that would work hand-in-hand with the electronic medical record for more precise documentation of cases, and aid in medical decision-making as well as rapid, accurate diagnoses. It would also include machine learning capabilities as more cases are fed into the system.

VISUALIZATIONS OF SOCIAL COMMUNICATION BEHAVIOR OF CHILDREN WITH AUTISM

Investigators: Karrie Karahalios, PhD, UIUC; Siraj Siddiqi, MD, OSF HealthCare; David Forsyth, PhD, UIUC; Mark Hasegawa-Johnson, PhD, UIUC; Hedda Meadan, PhD, BCBA-D, UIUC

Given that many children with autism spectrum disorder have deficits and delays in communication skills, researchers have been exploring ways to diagnose children early and begin with interventions at a very young age. Much of this begins with improving communication between parents and clinicians. This project’s objective is to develop a series of digital, interactive and visual tools to do just that. The idea is that these visualizations could mitigate challenges in discussions between parents and providers.

EARLY DETECTION OF DEVELOPMENTAL DISORDERS VIA A REMOTE SENSING PLATFORM

Investigators: Nancy McElwain, PhD, UIUC; Susan Caldecott-Johnson, MD, UICOMP, OSF HealthCare Children’s Hospital of Illinois; Mark Hasegawa-Johnson, PhD, UIUC; Siraj Siddiqi, MD, OSF HealthCare; Romit Roy Choudhury, PhD, UIUC

Child mental, behavioral and developmental disorders often go undiagnosed and untreated, thus increasing risk of spiraling disturbance well beyond childhood. This project will provide “proof of concept” for continuous, unobtrusive, large-scale and automated monitoring of young children’s functioning within the home environment, using wearable sensors. In doing so, a long-term objective is to detect potential developmental disorders or delays before such problems become clinically significant.

COMMUNITY-BASED TELE-REHABILITATION HEALTH NETWORK FOR ROBOTIC STROKE THERAPY

Investigators: T. Kesavadas, UIUC; Dusan Stipanovic, PhD, UIUC; Anne Horowitz, OTR/L, CSRS, MSCS, OSF HealthCare

Existing robot-based rehabilitation systems lack effective methods to monitor and enforce a patients’ participation in therapy. We propose to develop a community-based, networked robotic therapy system. This system uses a home-based haptic interface for rehabilitation of fine motor skills, with assistance from a remote external agent, such as a therapist, caregiver or artificial intelligence, who monitors progress and accordingly modifies the therapy regimen.

MEDLANG PHASE IL: A CONCEPT MAPPING TOOL FOR CASE ANALYSIS BY MEDICAL STUDENTS AND RESEARCHERS

Investigators: William Cope, PhD, UIUC; Cheng Xiang Zhai, PhD, UIUC; Mary Kalantzis, PhD, UIUC; Richard Tapping, PhD, UICOMP; Yerko Berrocal, MD, UICOMP; Jessica Hanks, MD, OSF HealthCare, UICOMP; Meenakshy Aiyer MD, UICOMP, OSF HealthCare

This project extends the recently completed Jump ARCHES project in which the group prototyped MedLang, an ontology-based medical concept mapping tool. The goal is to apply the tool to the analysis of single medical cases by medical students and researchers, and the addition of an artificial intelligence (AI) component to its suggestion system. The benefits of this tool for medical students will be to provide a rigorous learning space for the development of critical clinical thinking and offer a web-based infrastructure which will allow speedy peer review of cases and their accompanying concept maps.

SOFT AND DEXTEROUS SERVICE ROBOT CONFIGURATIONS TO SUPPORT HEALTHCARE AT HOME FOR OLDER ADULTS

Investigators: Girish Krishnan, PhD, UIUC; Wendy Rogers, PhD, UIUC; Ryan Riech, MD, MPH, OSF HealthCare

An increasing number of older adults live independently but have health care conditions that must be managed – both chronic and acute. The goal of this project is to investigate the effectiveness of soft robotic configurations in offering effective telehealth solutions, and understanding the social and behavioral aspects of how a robot builds trust with its user.

OPTIMAL DEPLOYMENT OF CANCER PREVENTION THROUGH DIGITAL HEALTH WORKERS

Investigators: Sarah de Ramirez, MD, OSF HealthCare, UICOMP; Hyojung Kang, PhD, UIUC; Lavanya Marla, PhD, UIUC; Roopa Foulger, OSF HealthCare; Mackenzie McGee, MD, OSF HealthCare; Abby Lotz, OSF HealthCare; Melinda Cooling, APRN, OSF HealthCare

This project proposes to develop a Digital Health Worker (DHW) program to use multiple varying digital modalities to decrease the socio-economic and racial disparities in cancer screening and mortality, specifically with breast cancer. Through the use of data science, this project will explore the most effective ways to deploy digital interventions for the promotion of cancer screening among populations with historically low screening rates and high mortality rates. Data analysis will also help optimize the DHW program to maximize screening rates, and provide an understanding of how to apply these practices to other types of cancers—especially among underserved populations.

A TRAINING SIMULATOR FOR CLINICAL BREAST EXAMINATION (CBE)

Investigators: Anusha Muralidharan, UIUC; Dr. Sarah de Ramirez, MD, OSF HealthCare, UICOMP; Thenkurussi Kesavadas, PhD, UIUC; Rohit Bhargava, PhD, UIUC; Dr. Sandhya Pruthi, MD, Mayo Clinic; Kimberly Michelle Bolin, National Consortium of Breast Centers

This project proposes to develop a high-fidelity training simulator to train health professionals on clinical breast examination techniques. It will also provide clinical evaluation to result in diagnosis of breast cancer at earlier stages, resulting in improved outcomes when followed with timely and appropriate treatment. The project uses current state-of-the-art technology to improve training using real-time performance analysis and mimics a realistic environment, giving medical professionals the flexibility of practicing as many times as they want in order to master the skill.

7-TESLA MRI IMAGING OF SEVERE TRAUMATIC BRAIN INJURY

Investigators: Paul M. Arnold, MD, FACS, Carle Foundation Hospital; Andrew Webb, PhD, Carle Foundation Hospital; Ravishankar Iyer, PhD, UIUC; Brad Sutton, PhD, UIUC; George Heintz, MSPH, MSE, UIUC; Dzung Dinh, MD, UICOMP, OSF HealthCare

The goal of this study is to image patients with traumatic brain injuries (TBI) by using high-field MRI, specifically the 7-Tesla. This type of imaging is expected to provide rich, previously unavailable information about lesions to diagnose what the effect of TBI could be. Better understanding of lesions can provide more detailed information about the extent of an injury and the cognitive processes that might be affected six months after injury. This will aid in the development of analytic tools to guide clinicians in decision-making and prognosis.

Partners in Jump ARCHES

Health Care Engineering Systems Center (HCESC) of the U of I Grainger College of Engineering provides clinical immersion and fosters collaboration between engineers and physicians. HCESC designs collaborative solutions to improve health care outcomes utilizing their expertise in simulation technologies, smart health systems, data analytics, human factors, and medical robotics. HCESC partners with Jump Simulation of OSF HealthCare at Peoria, Illinois, in this innovative relationship of Applied Research for Community Health through Engineering and Simulation (ARCHES). Learn more about HCESC at https://healtheng.illinois.edu/

Illinois – Grainger College of Engineering: As one of the world’s top ranked engineering programs, their students, faculty, and alumni set the standard for excellence. The College is focused on driving the economy, reimagining engineering education, and bringing revolutionary ideas to the world. They work to solve the world’s greatest challenges and look toward the future to find ways to make it a reality. Learn more about the College of Engineering at https://engineering.illinois.edu/

OSF HealthCare is an integrated health system owned and operated by The Sisters of the Third Order of St. Francis, Peoria, Illinois. OSF HealthCare employs more than 23,600 Mission Partners in 147 locations, including 14 hospitals – 10 acute care, four critical access – with 2,097 licensed beds, and 2 colleges of nursing throughout Illinois and Michigan. The OSF HealthCare physician network employs more than 1,500 primary care, specialists and advanced practice providers, who are part of the OSF Medical Group . OSF HealthCare, through OSF Home Care Services, operates an extensive network of home health and hospice services. It also owns Pointcore Inc., comprised of health care-related businesses; OSF HealthCare Foundation, the philanthropic arm for the organization; and OSF Ventures, which provides investment capital for promising health care innovation startups.

University of Illinois College of Medicine Peoria (UICOMP) educates 244 medical students and nearly 300 physician residents annually. The College of Medicine is home to the Cancer Research Center, the Center for Outcomes Research, and a collaborator in Jump Simulation. Learn more about UICOMP at http://peoria.medicine.uic.edu

Jump Simulation
, a part of OSF Innovation, is a collaboration between University of Illinois College of Medicine at Peoria and OSF HealthCare. The Jump center replicates a variety of patient care settings to ensure novice and seasoned clinicians can practice handling medical situations in a life-like environment. Boasting six floors and 168,000 square feet, the center is one of the largest of its kind and provides space for conferences, anatomic training, virtual reality and innovation. For more information, visit www.jumpsimulation.org.

The Center for Social and Behavioral Science (CSBS) was created to help address some of the grand challenges facing society that can be answered using the deep social and behavioral science expertise housed at the University of Illinois at Urbana-Champaign. In particular, the CSBS focuses on three grand challenges 1) solving poverty, 2) understanding the effect of technology on society, and 3) the role of social and behavioral factors in health. More information can be found at https://csbs.research.illinois.edu/

View more Jump ARCHES projects:

Spring 2021

Spring – COVID-19 PRIORITY CALL

2019

2018

2017

2016

2015